History
Bizen Chemical Co., Ltd. has been a pioneer in the production of supplements,
well before nutritional supplements became a mainstay in Japan.
1971 to 1980
- 1971 - Establishment of
Bizen Chemical Co., Ltd.
- Development technology
Patent acquisition -
- 1975 - Development of high-concentration vitamin E
- 1979 - Development of natural α-tocopherol as API
- Dietary supplements
Food ingredients
Pharmaceuticals -
- 1975 - “Bitapol E” natural vitamin E dietary supplement
- 1978 - “Bitapol E Facial Oil” basic cosmetic containing natural vitamin E
- 1980 - “E-Cap Nature” and “Vitalux E” natural vitamin E pharmaceuticals
- Factories and equipment
-
- 1975 - Installation of oil and lipid refining equipment (molecular distillation machine) (currently Factory No. 1)
1981 to 1990
- 1981 - 9 million yen capital increase,
for a total capital of 12 million yen
- Development technology
Patent acquisition -
- 1985 - Patent: Oyster extract powder and its manufacturing method
- 1986 - Patent: Health drink consisting of guava leaf extract
- Dietary supplements
Food ingredients
Pharmaceuticals -
- 1982 - “Oyster Extract” and “Rich Series” dietary supplements
- 1982 - “Oyster Extract Powder” food ingredients
- 1983 - “Guava Leaf Extract” and “EPA Bizen” dietary supplements
- 1983 - “Guava Leaf Extract Powder” food ingredients
- 1984 - “Garlic Extract Powder” food ingredients
- 1986 - “Soyaku” and “Tocostanin” pharmaceutical and nutritional tonics
- 1988 - “Gymnema Extract Powder” food ingredients
- 1988 - “Vizelux High” and “E-Cap Gold” pharmaceuticals/natural vitamin E agents
- 1990 - “Rhythmran” and “Rhythmran White” pharmaceutical dietary fiber plantago psyllium preparation
- 1990 - “Vizeluck EC” pharmaceutical vitamin E and C (principal agents) preparation
- Factories and equipment
-
- 1983 - Construction of Factory No. 2 (formulation manufacturing factory)
- 1989 - Construction of Factory No. 3 (formulation manufacturing factory, currently the General R&D Center)
- 1990 - Expansion of Factory No. 2 (formulation manufacturing factory)
1991 to 2000
- 1998 - Participated in Bitapol Co., Ltd.
- 2000 - Tokyo branch office opened
- Main
Development technology
Patent acquisition -
- 1992 - Patent: Method for manufacturing odorless garlic extract
- 1996 - Patent: Method for manufacturing hard granules containing vitamin C
- 1997 - Patent: α-amylase inhibitor
- 1999 - Patent: Method for extracting animal and plant extracts by destruction of frozen cell membrane
- Main
Dietary supplements
Food ingredients
Pharmaceuticals -
- 1992 - “Bizen DHA” dietary supplement
- 1994 - “Agaricus Blazei Extract Powder” food
ingredients
“Active DHA-O (DHA-rich egg yolk oil)” - 1998 - “Maitake Mushroom Extract Powder” and “Senna Stem Extract Powder” food ingredients
- 1998 - Mass production of EPA-E 98% as API
- Factories and equipment
-
- 1992 - Construction of Factory No. 5 (food ingredients/extract manufacturing factory)
- 1995 - Construction of new Factory No. 3 (formulation
manufacturing factory),
renovation of existing Factory No. 3 into General R&D Center - 1998 - Construction of Factory No. 6 (2 buildings) (oil and lipid extraction and refining factory) and attached office building
- Awards and certifications
-
- 1998 - Medium and Small Business Research Institute Award (Chugoku/Shikoku Area)
2001 to 2010
- 2008 - 38 million yen capital increase,
for a total capital of 50 million yen
- Main
Development technology
Patent acquisition -
- 2002 - Patent: Method for producing DHA-rich egg yolk oil
- 2004 - Patent: Mineral-rich oyster extract and its manufacturing method
- 2008 - Patent: Improved method for extraction of guava leaf extract
- 2009 - Patent: Agaricus polysaccharide protein composition by low temperature extraction and its manufacturing method
- Dietary supplements
Food ingredients
Pharmaceuticals -
- 2001 - “Marine Zinc S (zinc fortified oyster extract)” food ingredients
- 2002 - “Guava Phenone II (high polyphenol guava leaf extract)” food ingredients
- 2003 - “Aomori Garlic Extract Powder” food ingredients
- 2008 - “Miyazaki Bitter Melon Juice Powder” food ingredients
- Factories and equipment
-
- 2001 - Expansion of Factory No. 6 (Warehouse No. 1, changing room)
- 2006 - Phase 2 expansion of Factory No. 6 (Distillation Towers No. 3 and 5)
- 2010 - Purchase of farm land in Hiruzen, Okayama Prefecture for in-house production of raw material agricultural products
- Awards and certifications
-
- 2005 - Good Manufacturing Practice (GMP) certification for dietary supplements (Japan Health and Nutrition Food Association)
- 2006 - ISO 9001 (British Standards Institution (BSI) Japanese subsidiary)
- 2007 - HALAL certification for DHA-rich refined oil
- 2007 - FDA-HACCP certification (Japan Fisheries Association)
2011 to 2020
- 2020 - 50-year anniversary of establishment
of Bizen Chemical Co., Ltd.
- Main
Development technology
Patent acquisition -
- 2014 - Patent: Method for obtaining highly unsaturated fatty acid derivatives
- 2016 - Patent: Oyster hot water extract
- 2018 - Patent: Composition for prevention and/or treatment of eye strain and/or dry eye
- 2018 - Patent: Method for producing high-purity omega-3 fatty acid ethyl ester
- 2019 - Patent: Method for manufacturing high-purity and high-yield highly unsaturated fatty acids
- 2019 - Development of “B-ReC” gastrointestinal delivery tablet
- 2020 - Development of “B-MoG” intraoral retention granules
- Main
Dietary supplements
Food ingredients
Pharmaceuticals -
- 2012 - “Blueberry Leaf Extract Powder” food
ingredients
“DC-15 Extract Powder (product fermented with natto bacteria)” - 2016 - First acceptance of notification for food with functional claims, for food product with stress relief functions
- 2016 - “Maca Extract Powder” food ingredients
- 2017 - “DHA no Kiwami 1000mg Plus W” food product with functional claims
- 2018 - “DHA70 BAPT” food ingredients
- 2018 - Start of EPA final API manufacturing business
- 2019 - “UKOGIN (Siberian ginseng extract)” food ingredients
- 2020 - “L8020 Lactobacillus Powder,” “SAC
Garlic,” “Cao Bang Tea Extract Powder,” and
“EPA70 BAPT” food ingredients
- 2012 - “Blueberry Leaf Extract Powder” food
ingredients
- Factories and equipment
-
- 2011 - Phase 3 expansion of Factory No. 6 (Warehouse No. 2, Distillation Tower No. 6)
- 2012 - Phase 4 expansion of Factory No. 6 (EPA Plant No. 5)
- 2013 - Phase 5 expansion of Factory No. 6 (Distillation Towers No. 7 and 8)
- 2013 - Introduction of solar power generation system
- 2014 - Introduction of equipment for food defense (vein authentication, cameras, etc.)
- 2014 - Introduction of fully automated line for filling, packaging, and boxing sticks (robot arm, etc.)
- 2019 - Phase 6 expansion of Factory No. 6 (API section)
- Awards and certifications
-
- 2011 - EU-HACCP certification (Ministry of Health, Labour and Welfare)
- 2015 - Japan Health and Nutrition Food Association Award
2021 to present
- 2021 - Establishment of our corporate mission
“Creating new value by using original technology
to support people’s health”
- Development technology
Patent acquisition -
- 2021 - Development of “B-HiT” high content tableting technology
- 2021 - Patent: Method for chemical conversion of unsaturated fatty acids by carbon chain extension reaction
- 2022 - FSSC 22000 (British Standards Institution (BSI) Japanese subsidiary)
- Awards and certifications
-
- 2022 - Japan Society for Bioscience, Biotechnology, and Agrochemistry, Chugoku-Shikoku Branch Technology Award (B-ReC formulation technology)
